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Previous Pathology Case Challenges

  • Left Flank

    A 47-year-old woman presents with a 12 cm left flank mass. Computed tomography scan shows a deep seated homogenous well-circumscribed mass.

  • Lung

    A 70-year-old woman with a long history of smoking presents with weight loss, cough, and shortness of breath of several months’ duration.

  • Liver

    A 70-year-old man presents with vague abdominal pain and increasing jaundice. His past medical history is notable for chronic hepatitis C.

  • Kidney

    A 50-year-old man presents with longstanding hematuria and flank pain, and a right renal mass with retroperitoneal lymphadenopathy is identified on CT scan.

  • Heart

    A 6-month-old baby boy presents to an outside hospital with cardiomyopathy of uncertain etiology. Cardiac transplantation is performed.

  • Pleural Fluid

    A 54-year-old man with long-standing diabetes mellitus, chronic renal failure, and no previous history of malignancy presented with shortness of breath. His chest x-ray revealed large bilateral pleural effusions but no lung masses or adjacent lymphadenopathy.

  • Cranium

    A 65-year-old right-handed woman with a long-standing history of headaches presents to the emergency room after having a witnessed seizure.

  • Pancreas

    A 45-year-old woman presents to her internist with fatigue, constipation, dry skin, weight gain, and mild difficulty in swallowing over the past few months.

  • Thyroid

    A 45-year-old woman presents to her internist with fatigue, constipation, dry skin, weight gain, and mild difficulty in swallowing over the past few months.

  • Placenta

    A 28-year-old woman with prenatal history of oligohydramnios delivers an infant with polycystic kidney disease at 35 weeks’ gestation.

  • Spleen

    A 56-year-old man presents with a six-month history of unintentional weight loss, persistent fever, and night sweats. A complete blood count indicates anemia and thrombocytosis.

  • Heart

    A 50-year-old man presents to the ER with diffuse abdominal pain. His abdomen is markedly tender to palpation with significant guarding.

  • Small Intestine

    A 50-year-old man presents to the ER with diffuse abdominal pain. His abdomen is markedly tender to palpation with significant guarding.

  • Adrenal Gland

    A healthy, athletic 15-year-old girl is hit by a car while riding her bike, sustaining minor injuries. At the hospital, a CT scan demonstrates a left adrenal gland mass.

  • Spleen

    A 62-year-old man presents with sudden onset dizziness. In the emergency department, he appears lethargic and pale.

  • Adrenal Gland

    A 56-year-old woman presents with abdominal pain, bloating, and early satiety of several months’ duration.

  • Mediastinum

    A 60-year-old woman is involved in a motor vehicle accident and is admitted to the emergency department for evaluation of pleuritic chest pain complaints.

  • Soft Tissue of the Chest Wall

    A 55-year-old woman presents with non-productive cough of several- weeks duration. Computerized tomography shows a 9 x 9 cm mass of the left chest wall.

  • Adrenal Gland

    A 45-year-old woman presents to her internist with back pain for the past few months. A high level of DHEA-S in her serum is detected.

  • Pelvis

    A 35-year-old asymptomatic woman presents for a routine pelvic exam. Her gynecologist notes fullness within the pelvis and orders an MRI.

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