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Previous Pathology Case Challenges

  • Small Intestine

    A 21-year-old woman presents with intractable severe abdominal pain with nausea and vomiting. The patient’s history includes previous episodes of “upset stomach” and associated diarrhea.

  • Left Kidney

    A 53-year-old diabetic woman presents with gross hematuria, fever, and flank pain. She has a history of recurrent urinary tract infections.

  • Retroperitoneum

    A 12-month-old boy presents with an enlarged abdomen during a routine checkup. Abdominal ultrasound reveals a 6 cm left adrenal/paraspinal mass.

  • Adrenal Gland

    A 12-month-old boy presents with an enlarged abdomen during a routine checkup. Abdominal ultrasound reveals a 6 cm left adrenal/paraspinal mass.

  • Kidney

    A 1-month-old boy presents with a 10 cm solid abdominal mass centered in his right kidney (identified by imaging).

  • Ovary

    A 74-year-old woman with no prior history of cancer presents with a large abdominal mass. Pelvic ultrasound identifies a left adnexal mass.

  • Retroperitoneum

    A 47-year-old man presents with abdominal fullness, jaundice, and fatigue. Physical exam reveals multiple spider angiomata on the surface of his abdomen and large volume ascites.

  • Liver

    A 47-year-old man presents with abdominal fullness, jaundice, and fatigue. Physical exam reveals multiple spider angiomata on the surface of his abdomen and large volume ascites.

  • Ovary

    A 45-year-old nulliparous woman presents with a history of mild abdominal pain of 3 months’ duration. Ultrasound reveals a 10 cm right adnexal mass.

  • Kidney

    A 4-year-old girl is found to have an abdominal mass. Computed tomography scan confirms the presence of a solid and focally cystic left renal mass.

  • Abdomen

    A 45-year-old man presents with a history of abdominal discomfort. Radiologic studies reveal a relatively well-defined 12 cm mass abutting the left adrenal gland.

  • Breast

    A 67-year-old woman presents with a vague area of thickening in her left breast. Mammographic imaging is unremarkable, and ultrasound reveals an ill-defined mass which is excised.

  • Ovary

    A 51-year-old woman presents with abdominal discomfort and ascites. Imaging studies reveal bilateral ovarian masses.

  • Liver

    A 63-year-old woman presents with abdominal pain and swelling of several weeks’ duration. Radiologic imaging reveals an 11 cm heterogenous mass in the liver.

  • Spleen

    A 68-year-old man with a 3-week history of abdominal discomfort presents to the emergency department. Ultrasound reveals a massively enlarged spleen.

  • Peripancreatic Lymph Node

    A 58-year-old woman presents with diarrhea. Esophagogastroduodenoscopy reveals multiple ulcers throughout the upper gastrointestinal tract.

  • Thigh

    A 36-year-old man presents with an enlarging mass in his thigh. Physical exam demonstrates a large, firm, fusiform mass in the deep anterior thigh.

  • Breast

    A 55-year-old woman with a history of lung carcinoma presents with a 13 cm breast mass.

  • Uterine Cervix

    A 17-year-old girl presents with complaints of irregular vaginal bleeding. On clinical exam, she has a gelatinous multi-lobulated lesion protruding from the cervical os.

  • Retroperitoneum

    A 70-year-old woman presents with increasing abdominal girth, discomfort, and bilateral leg swelling over several months.

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