Previous Pathology Case Challenges

A 2-year-old boy presents with a history of a rapidly progressing tumor of the urinary bladder and normal serum alpha-fetoprotein.

A 60-year-old man presents with six months of epigastric pain that radiates to his back, as well as weight loss and jaundice.

A 66-year-old woman with no history of other malignancies presents with a palpable 10-cm mass in the right breast.

A 60-year-old woman presents with a 3.7 cm breast mass and multiple purple skin lesions that are more prominent around the nipple and areolar region.

A 30-year-old G1P0 woman with limited prenatal care presents with vaginal bleeding at 15 weeks’ gestation. There is no evidence of fetal development on ultrasound.

A 58-year-old man presents with ​a ​5-year history of a painless, slow-growing subcutaneous mass in the inguinal region

A 69-year-old non-smoking Japanese woman ​presents ​with a history of multiple symptoms resembling​ ​transient ischemic attacks​. She​ undergoes a right lung middle lobectomy for a 6.5 cm subpleural, well​-​circumscribed mass.

A 30-year-old G1P1 woman from Arizona delivers a stillborn fetus at 27 weeks’ gestation. The untrimmed placenta weighs 233 grams and shows multiple infarcts.

A 22-year-old man with a history of colectomy presents with abdominal pain. Physical exam finds a palpable abdominal mass, which a CT scan confirms.

A 46-year-old woman presents with pelvic pain and abnormal vaginal bleeding. Endometrial biopsy shows proliferative endometrium.

A 45-year-old man presents with bilateral gynecomastia. On physical examination, a left testicular mass is identified.

A 62-year-old man presents with a painless testicular mass. A radical orchiectomy is performed, revealing a solid lobular tan mass measuring 4 cm.

A 67-year-old man presents with diarrhea, nausea, and intermittent fever. His medical history includes a thyroid carcinoma and a melanoma on his upper back, widely excised.

A 32-year-old woman undergoing antenatal care has an abdominal wall nodule measuring 2 cm early mid-trimester, which increases to 5 cm in the third trimester.

A 47-year-old woman with a history of sickle cell disease presents with increasing abdominal pain. A CBC demonstrates anemia and a CT scan reveals bilateral adrenal masses.

A 19-year-old otherwise healthy man presents with a history of intermittent pain associated with an enlarging left neck mass.

A 3-year-old boy presents with a 12 cm solid heterogeneous mass within his right kidney.

A 62-year-old man presents with hematuria and flank pain. A computed tomography scan shows a 6 cm mass in the right kidney.

A 60-year-old woman presents​ ​with shortness of breath and recent onset of weight loss. She expires shortly after admission.

A 6-year-old girl with a history of persistent asthma is brought to urgent care with 5 days of cough and cold symptoms. She is in cardiopulmonary arrest.