Gynecologic Pathology


Gynecologic pathology stands out due to the unique and diverse diseases that affect multiple organs within the reproductive system—including the cervix, endometrium, myometrium, ovary, and fallopian tubes. This subspecialty offers a wide range of cases, from benign to malignant, with complex differentials and challenging benign mimics. The close collaboration with gynecological oncologists fosters a robust team dynamic, making the field both intellectually stimulating and rewarding.

Frequently Asked Questions

Despite the high demand, there is actually a shortage of gynecologic subspecialists, which can lead to increased responsibilities for newly trained pathologists. Moreover, employment challenges in gynecologic pathology vary rather dramatically based on one's practice settings. In some academic, community, or private practices, there may be fewer options due to the limited number of subspecialists, and the variable case volume often requires coupling gynecologic pathology with another subspecialty for a more consistent workload. Additionally, some settings may not offer exclusive signing out of gynecologic pathology, potentially impacting job satisfaction.

On-call time varies depending on the practice setting. During fellowship, on-call duties are generally not required. However, on-call responsibilities may be necessary in practice, particularly for frozen sections and after-hours consultations. This is similar to other anatomical pathology subspecialties where on-call duties may or may not be part of the practice depending on the institution's needs.

Although it may not be as high as other surgical specialties, gynecologic pathology typically involves a solid volume of cases that varies based on the institution, particularly with regard to common specimens like cervical and endometrial biopsies. Caseloads also impact the volume of resection specimens, and the complexity of cases is increasing, often necessitating immunohistochemistry (IHC) and occasionally molecular testing for accurate diagnoses and staging, especially in areas like mesenchymal smooth muscle tumors and endometrial cancers following new staging guidelines. Ancillary testing, such as IHC and molecular tests, is commonly performed to aid in diagnoses.

It interacts closely with several medical specialties, including gynecologic oncology, gynecology and obstetrics, radiology, urogynecology, and reproductive endocrinology and infertility.

It pairs well with several other subspecialties, including breast, obstetrical/perinatal, genitourinary, and cytology (especially for pap smears). Additionally, it can also complement expertise in bone & soft tissue, molecular, and dermatopathology for comprehensive patient care.

While there are instances where gynecologic pathologists may engage with patients—such as in cases of perinatal loss where sensitive discussions or consultations are required—this subspecialty typically has minimal direct interaction. However, some pathologists may interact with patients upon request, such as when patients want to view their pathology slides or during telehealth appointments facilitated by gynecologic oncologists to explain diagnoses. These interactions are usually limited but can provide valuable insights and experiences for both pathologists and patients.

  • Pathology Case Challenge: Ovary

    Review whole slide images to assess your knowledge and determine the diagnosis.

  • Pathology Case Challenge: Uterine Cervix

    Test your knowledge using a virtual microscope whole slide image of a surgical specimen to diagnose diseases.

  • Cytopathology Topic Center

    Resources and educational material from the CAP in the field of gynecologic pathology.

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