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Pathology Case Challenge

This program offers at least two challenging cases each month from the CAP Performance Improvement Program in Surgical Pathology. For each case, you will use a virtual microscope whole slide image of a surgical specimen to diagnose diseases.

You will be presented with information on each case including: specimen source, clinical history, laboratory findings, and a representative whole slide image of the surgical specimen. After you complete each case, you will receive a case summary with three multiple-choice questions that relate to the case.

Please note: DigitalScope® is supported with Microsoft Internet Explorer 11.0 (limited support for IE 9 and 10) or later, or FireFox 4.0 or later, or Safari 3 or the latest Google Chrome version.


Uterus

A 46-year-old woman presents with pelvic pain and abnormal vaginal bleeding. The patient undergoes an endometrial biopsy, which shows proliferative endometrium. She subsequently undergoes a total hysterectomy. On gross exam, the uterus is enlarged, weighing 606 gm. The cut surface shows a 10- cm, yellow myometrial mass permeating through the myometrium, which is cobblestoned in appearance with fibrotic bands​​​​. The lesion is diffusely positive for CD10, while negative for desmin.​​​​​​​​​​ Fluorescence in situ hybridization testing reveals a JAZF1::SUZ12 translocation.

Read the Pathology Case Challenge

Previous Case Challenges

View a list of previous cases using the virtual microscope to examine various surgical specimens and diagnose diseases.

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